Laboratory Finding in Fructose Malabsorption
The main danger of fructose malabsorption is the malnutrition associated with it. Important nutrients like calcium and iron are often deficient. Fructose malabsorption therefore is not only associated with gastro-intestinal distress but also the inability to absorb all kinds of nutrition which can lead to serious diseases like anaemia and osteoporosis. Since over consumption of fructose can cause diarrhea, micronutrients can be flushed out from small intestine before even having a chance to be absorbed. This can then lead to various nutrient deficiences, especially over time. Plasma levels of zinc, iron, calcium, vitamin C and E and triptophan may also be lowered. Amylase, lipase and triglicerides may be elevated. Testing reveals widely reported decreased levels of folic acid, zinc and tryptophan in the blood.
Fructose malabsorption is associated with lower serum zinc concentrations. Zinc, an essential mineral required by the body for maintaining a sense of smell, keeping a healthy immune system, building proteins, triggering enzymes, and creating DNA. Zinc also helps the cells in your body communicate by functioning as a neurotransmitter. Gastrointestinal malabsorption can also lead to zinc deficiency symptoms. Chronic diarrhea is one of the most common symptoms of fructose malabsorption. Patients with chronic diarrhea are known to exhibit signs of zinc deficiency. Inadequate intake of zinc in the daily diet is the main reason why zinc deficiencies happen and other than malabsorption can also be promoted by an increase in the losses of zinc from the body, such as when copper exposure is high, and when your body requirement for zinc increases (such as when lactating or pregnant). Zinc deficiency can also be due to acrodermatis enteropathica, chronic renal disease, sickle cell disease, diabetes, malignancy, chronic liver disease and other chronic illnesses. The symptoms of zinc deficiency are quite diverse. Zinc deficiency plays a role in cellular turnover of the gastrointestinal mucosa and also has been linked to poor appetite and mental disturbances. Zinc deficiency during pregnancy can negatively affect both the mother and fetus. A deficiency in zinc can lead to stunted growth, hair loss, mild anemia, hyperactivity, diarrhea, impotence, and depressed immunity. Conversely, consuming too much zinc can disrupt absorption of copper and iron, as well as create large amounts of toxic free radicals. The current RDA for Zinc is 15mg.
Symptoms of zinc deficiency
Not all symptoms appear in all individuals with a deficiency.
Hair loss
Behavioral and sleep disturbances
Dandruff
Hang nails
Eye and skin lesions
Change in appetite
Depressed immunity
Delay in wound healing
Mental disturbences
Skin lesions such as eczema, psoriasis and acne
Growth retardation
Mild anemia
Increased allergic sensitivity
Inflammation of your nail cuticles
Pre-eclampsia (toxaemia) in pregnancy and post-natal depression
Skin dryness and rashes
Reduced fertility
Hyperactivity
Diarrhea
Pre-menstrual syndrome, disturbance in your menstrual cycle
Inflammatory bowel disease
Poor appetite
Loss of sex drive
Loss of appetite
White spots on fingernails, transverse lines and poor nail growth
Loss of senses of taste or smell
Foods high in Zinc.
Avocado
Bananas
Beef
Blackberries
Brewers yeast
Chicken (dark meat)
Eggs
Fish
Kiwi fruit
Lamb
Liver
Olives
Oysters
Pork
Pumpkin seeds
Shellfish
Spinach
Strawberries
Sweet potatoes
Tomatoes
Turkey (dark meat)
Veal Liver
Fructose malabsorption is also associated with folic acid deficiency. Fructose malabsorption was found to be correlated with low levels of folic acid in blood plasma in some cases. This could be partly due to the fact that fructose malabsorption leads to a profound change in bacterial colonization, especially in the colon. Because a substantial amount of folic acid derives from intestinal bacteria, it seems reasonable that a change in the population of gastrointestinal bacteria could lead to a change in the plasma concentrations of folic acid. The deficiency could also be due to the fact that fructose malabsorption is known to accelerate gastrointestinal transit when patients are exposed to fructose, thus reducing the contact time that is necessary for the absorption of nutrients. Folic acid deficiency has been shown to increase the risk for development of neural tube defects in newborns. Folic acid deficiency may lead to diarrhea, depression, confusion and anemia.
Symptoms of Folic Acid deficiency
The signs of folate deficiency are often very subtle.
Symptoms include:
Weight loss
Loss of appetite
Irritablility
Behaviour disorders
Headaches
Weekness
Depression
Sore tongue
Heart palpitations
Anemia can be a sign of advanced folate deficiency.
Pregnant woman with folate deficiency who become pregnant are more likely to give birth to low birth weight and premature babies and babies with neural tube defects.
In infants and children, folate deficiency can slow growth rate.
Foods high in folic acid
Liver and liver products
Baker’s Yeast
Leafy vegetables such as spinach
Tryptophan Deficiency
Fructose as well as lactose malabsorption are associated with signs of mental depression, and behavior problems. Fructose malasorption and lactose cause improper absorption of tryptophan in the intestine and reduced levels of tryptophan in the blood. Tryptophan is one of the 20 standard amino acids, as well as an essential amino acid in the human diet. It is necessary for the production of serotonin and melatonin. Fructose in the lower intestine will bond with any tryptophan present, making it impossible for the sufferer's body to absorb this essential amino acid. Tryptophan is utilised by the body to create both melotonin (to aid in sleep) and serotonin (to aid in positive mood). Low levels of these neurotransmitters are associated with depression, anxiety, anger, lack of focus, rage, behavior problems and inconsistant sleep patterns. Tryptophan can soothe nerves and anxiety, reduce carbohydrate cravings, relieve premenstrual symptoms, and enhance relaxation and sleep.
Dietary sources
Foods high in tryptophan
Tryptophan is present in most protein-based foods or dietary proteins.
Poultry
Oats
Pumpkin seeds
Spirulina
Cottage cheese
Red meat
Eggs
Fish
The main danger of fructose malabsorption is the malnutrition associated with it. Important nutrients like calcium and iron are often deficient. Fructose malabsorption therefore is not only associated with gastro-intestinal distress but also the inability to absorb all kinds of nutrition which can lead to serious diseases like anaemia and osteoporosis. Since over consumption of fructose can cause diarrhea, micronutrients can be flushed out from small intestine before even having a chance to be absorbed. This can then lead to various nutrient deficiences, especially over time. Plasma levels of zinc, iron, calcium, vitamin C and E and triptophan may also be lowered. Amylase, lipase and triglicerides may be elevated. Testing reveals widely reported decreased levels of folic acid, zinc and tryptophan in the blood.
Fructose malabsorption is associated with lower serum zinc concentrations. Zinc, an essential mineral required by the body for maintaining a sense of smell, keeping a healthy immune system, building proteins, triggering enzymes, and creating DNA. Zinc also helps the cells in your body communicate by functioning as a neurotransmitter. Gastrointestinal malabsorption can also lead to zinc deficiency symptoms. Chronic diarrhea is one of the most common symptoms of fructose malabsorption. Patients with chronic diarrhea are known to exhibit signs of zinc deficiency. Inadequate intake of zinc in the daily diet is the main reason why zinc deficiencies happen and other than malabsorption can also be promoted by an increase in the losses of zinc from the body, such as when copper exposure is high, and when your body requirement for zinc increases (such as when lactating or pregnant). Zinc deficiency can also be due to acrodermatis enteropathica, chronic renal disease, sickle cell disease, diabetes, malignancy, chronic liver disease and other chronic illnesses. The symptoms of zinc deficiency are quite diverse. Zinc deficiency plays a role in cellular turnover of the gastrointestinal mucosa and also has been linked to poor appetite and mental disturbances. Zinc deficiency during pregnancy can negatively affect both the mother and fetus. A deficiency in zinc can lead to stunted growth, hair loss, mild anemia, hyperactivity, diarrhea, impotence, and depressed immunity. Conversely, consuming too much zinc can disrupt absorption of copper and iron, as well as create large amounts of toxic free radicals. The current RDA for Zinc is 15mg.
Symptoms of zinc deficiency
Not all symptoms appear in all individuals with a deficiency.
Hair loss
Behavioral and sleep disturbances
Dandruff
Hang nails
Eye and skin lesions
Change in appetite
Depressed immunity
Delay in wound healing
Mental disturbences
Skin lesions such as eczema, psoriasis and acne
Growth retardation
Mild anemia
Increased allergic sensitivity
Inflammation of your nail cuticles
Pre-eclampsia (toxaemia) in pregnancy and post-natal depression
Skin dryness and rashes
Reduced fertility
Hyperactivity
Diarrhea
Pre-menstrual syndrome, disturbance in your menstrual cycle
Inflammatory bowel disease
Poor appetite
Loss of sex drive
Loss of appetite
White spots on fingernails, transverse lines and poor nail growth
Loss of senses of taste or smell
Foods high in Zinc.
Avocado
Bananas
Beef
Blackberries
Brewers yeast
Chicken (dark meat)
Eggs
Fish
Kiwi fruit
Lamb
Liver
Olives
Oysters
Pork
Pumpkin seeds
Shellfish
Spinach
Strawberries
Sweet potatoes
Tomatoes
Turkey (dark meat)
Veal Liver
Fructose malabsorption is also associated with folic acid deficiency. Fructose malabsorption was found to be correlated with low levels of folic acid in blood plasma in some cases. This could be partly due to the fact that fructose malabsorption leads to a profound change in bacterial colonization, especially in the colon. Because a substantial amount of folic acid derives from intestinal bacteria, it seems reasonable that a change in the population of gastrointestinal bacteria could lead to a change in the plasma concentrations of folic acid. The deficiency could also be due to the fact that fructose malabsorption is known to accelerate gastrointestinal transit when patients are exposed to fructose, thus reducing the contact time that is necessary for the absorption of nutrients. Folic acid deficiency has been shown to increase the risk for development of neural tube defects in newborns. Folic acid deficiency may lead to diarrhea, depression, confusion and anemia.
Symptoms of Folic Acid deficiency
The signs of folate deficiency are often very subtle.
Symptoms include:
Weight loss
Loss of appetite
Irritablility
Behaviour disorders
Headaches
Weekness
Depression
Sore tongue
Heart palpitations
Anemia can be a sign of advanced folate deficiency.
Pregnant woman with folate deficiency who become pregnant are more likely to give birth to low birth weight and premature babies and babies with neural tube defects.
In infants and children, folate deficiency can slow growth rate.
Foods high in folic acid
Liver and liver products
Baker’s Yeast
Leafy vegetables such as spinach
Tryptophan Deficiency
Fructose as well as lactose malabsorption are associated with signs of mental depression, and behavior problems. Fructose malasorption and lactose cause improper absorption of tryptophan in the intestine and reduced levels of tryptophan in the blood. Tryptophan is one of the 20 standard amino acids, as well as an essential amino acid in the human diet. It is necessary for the production of serotonin and melatonin. Fructose in the lower intestine will bond with any tryptophan present, making it impossible for the sufferer's body to absorb this essential amino acid. Tryptophan is utilised by the body to create both melotonin (to aid in sleep) and serotonin (to aid in positive mood). Low levels of these neurotransmitters are associated with depression, anxiety, anger, lack of focus, rage, behavior problems and inconsistant sleep patterns. Tryptophan can soothe nerves and anxiety, reduce carbohydrate cravings, relieve premenstrual symptoms, and enhance relaxation and sleep.
Dietary sources
Foods high in tryptophan
Tryptophan is present in most protein-based foods or dietary proteins.
Poultry
Oats
Pumpkin seeds
Spirulina
Cottage cheese
Red meat
Eggs
Fish
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